Video: Puas yog exosomes qia hlwb?
2024 Tus sau: Stanley Ellington | [email protected]. Kawg hloov kho: 2023-12-16 00:17
Exosomes yog nano-sized vesicles uas muaj roj ntsha signaling molecules uas kho cell – cell teeb liab. Mesenchymal qia hlwb (MSCs) ntseeg tau tias muaj cov nyhuv antitumor thiab nyiam rau lawv cov khoom, xws li lub cev tiv thaiv kab mob thiab muaj peev xwm mus khaws cia ntawm qhov chaw qog.
Kuj tseem paub yog, vim li cas exosomes zoo dua li cov qia hlwb?
Hauv cov ntsiab lus, exosomes tuaj yeem tso tawm los ntawm ntau hom qia hlwb thiab muaj peev xwm hloov kho qhov ua haujlwm ntawm receptor hlwb thiab cov ntaub so ntswg. Piv nrog qia hlwb , uas yuav ua rau txawv txawv txawv thiab qog tsim, lub exosomes kev kho kom haum xeeb harbors lub neej yav tom ntej.
Tom qab, lo lus nug yog, dab tsi yog exosomes raws nraim? Exosomes yog membrane bound extracellular vesicles (EVs) uas yog tsim nyob rau hauv endosomal compartment ntawm feem ntau eukaryotic hlwb. Lub cev multivesicular (MVB) yog ib qho endosome txhais los ntawm intraluminal vesicles (ILVs) uas bud sab hauv mus rau hauv lub endosomal lumen.
Kuj paub yog, dab tsi yog exosomes txhaj tshuaj?
Suntanner, kho koj tus kheej: Exosome Kev kho mob tuaj yeem pab kho lub hnub zoo dua, muaj hnub nyoog ntawm daim tawv nqaij. Tsis tas li ntawd, qhov loj ntawm nanometer exosomes tuaj yeem xa mus rau lub hom phiaj hlwb ntawm rab koob-dawb txhaj tshuaj . Exosomes yog cov hnab me me (30 - 150 nanometers thoob plaws) uas tau tawm thiab coj los ntawm cov hlwb.
Dab tsi yog exosomes siv rau?
Exosomes yog cov lipid me me uas zais los ntawm ntau lub hlwb. Lawv tau pib xav tias yuav muab cov hlwb nrog lub ntsiab lus pov tseg cov proteins uas tsis xav tau, nucleic acids, thiab lipids. Txawm li cas los xij, exosomes ua tam sim no paub tias ua lub luag haujlwm hauv kev sib txuas lus intercellular.
Pom zoo:
Puas muaj kev cuam tshuam rau koj lub hlwb?
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