Vim li cas enzyme induction tseem ceeb?
Vim li cas enzyme induction tseem ceeb?

Video: Vim li cas enzyme induction tseem ceeb?

Video: Vim li cas enzyme induction tseem ceeb?
Video: Li Cas Poob Lub Plab Muaj Roj 1 Lub Limtiam? 2024, Kaum ib hlis
Anonim

Enzyme induction yog ib qho ntawm feem ntau tseem ceeb cov txheej txheem hauv qab kev sib cuam tshuam tshuaj lom neeg (Conney 1967, 1982; Kedderis 1990). Kev raug rau ntau yam tshuaj lom neeg ib puag ncig tuaj yeem induce xenobiotic metabolism, suav nrog cov pa phem, haus luam yeeb, thiab cov khoom noj khoom haus.

Nyob rau hauv tas li ntawd, lub enzyme induction txhais li cas?

Enzyme induction yog ib tug txheej txheem nyob rau hauv uas ib tug molecule (piv txwv li ib tug tshuaj) induces (piv txwv li pib los yog txhim khu kev qha) qhia ntawm ib tug enzyme . Enzyme inhibition ua tau xa mus rau. inhibition ntawm kev qhia ntawm lub enzyme los ntawm lwm molecule.

Dab tsi yog enzyme induction thiab kev tsim txom? Enzyme induction yog ib txoj kev uas ib enzyme yog tsim nyob rau hauv teb rau lub xub ntiag ntawm ib tug tshwj xeeb molecule. Hauv cov kab mob, cov lactose (lac) operon yog ib qho zoo heev uas ua haujlwm ntawm lub hauv paus ntawm induction . Enzyme tiv thaiv yog thaum lub repressor molecules tiv thaiv kev tsim khoom ntawm ib qho enzyme.

Kuj tseem xav paub, dab tsi ua cov enzyme inducers?

Ib enzyme inducer yog ib hom tshuaj uas ua rau kom cov metabolism hauv ib qho enzyme los yog khi rau lub enzyme thiab ua kom nws, lossis los ntawm kev nthuav qhia cov noob coding rau cov enzyme.

Dab tsi yog microsomal enzyme?

Microsomal enzymes Feem ntau pom muaj nyob rau hauv endoplasmic reticulum ntawm hepatocytes. Cytochrome P450 thiab NADPH cytochrome c reductase yog ob lub ntsiab cov enzymes hauv qhov system no. Cytochrome P450 khi rau oxygen, thaum lub reductase shuttles electrons ntawm NADPH rau cytochrome P-450.

Pom zoo: