Lub hom phiaj ntawm non oxidative theem ntawm pentose phosphate txoj kev yog dab tsi?
Lub hom phiaj ntawm non oxidative theem ntawm pentose phosphate txoj kev yog dab tsi?

Video: Lub hom phiaj ntawm non oxidative theem ntawm pentose phosphate txoj kev yog dab tsi?

Video: Lub hom phiaj ntawm non oxidative theem ntawm pentose phosphate txoj kev yog dab tsi?
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Anonim

Cov tsis yog - oxidative theem tsim 5-carbon suab thaj, uas tuaj yeem siv rau hauv kev sib txuas ntawm nucleotides, nucleic acids, thiab amino acids. Cov pentose phosphate txoj kev yog lwm txoj hauv kev rau glycolysis.

Ntawm no, lub hom phiaj ntawm txoj kev pentose phosphate yog dab tsi?

Cov pentose phosphate txoj kev feem ntau yog catabolic thiab ua haujlwm ua lwm yam qabzib oxidizing txoj kev rau tiam ntawm NADPH uas yuav tsum tau rau txo cov biosynthetic tshuaj xws li cov cholesterol biosynthesis, bile acid synthesis, steroid hormone biosynthesis, thiab fatty acid synthesis.

Tsis tas li ntawd, dab tsi yog qhov pib compound rau pentose phosphate txoj kev? Kev tawg ntawm cov suab thaj yooj yim, qabzib, hauv glycolysis muab thawj 6-carbon molecule xav tau rau pentose phosphate txoj kev . Thaum thawj kauj ruam ntawm glycolysis, cov piam thaj hloov pauv los ntawm qhov sib ntxiv ntawm a phosphate pab pawg, tsim cov piam thaj-6- phosphate , lwm 6-carbon molecule.

Nyob rau hauv kev hwm rau qhov no, lub hom phiaj ntawm nonoxidative theem ntawm pentose phosphate shunt yog dab tsi?

Cov pentose phosphate txoj kev yog lwm txoj hauv kev rau glycolysis thiab tsim NADPH ( oxidative theem ) thiab pentoses (5-carbon qab zib, nonoxidative theem ). Nws kuj metabolizes kev noj haus pentoses thiab muab glycolytic/gluconeogenic intermediates.

Puas yog txoj kev pentose phosphate xav tau oxygen?

Lub PPP ua tsis haus lossis tsim ATP thiab ua tsis yog xav tau molecular oxygen . Nyob rau hauv thaum ntxov 'oxidative theem' ntawm PPP, thaum lub sij hawm uas thawj cov pa roj carbon monoxide lub cev pob txha ploj li carbon dioxide, nicotinamide adenine dinucleotide. phosphate (NADP+) hloov dua siab tshiab rau NADPH.

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