Video: Yuav tshem tawm vancomycin li cas?
2024 Tus sau: Stanley Ellington | [email protected]. Kawg hloov kho: 2023-12-16 00:17
Excretion: Intravenous vancomycin txhaj tshuaj yog feem ntau tshem tawm los ntawm glomerular pom nyob rau hauv lub raum (75% ntawm cov zis). Qhov ncauj vancomycin feem ntau tau excreted nyob rau hauv quav.
Piv txwv li, vancomycin puas tau dialyzed?
Vim vancomycin muaj qhov hnyav molecular ntawm kwv yees li 1500 Da, nws tsuas yog tshem tawm los ntawm cov pa hemodialysis, uas tso cai rau kev siv sijhawm ntev heev (piv txwv li, ib koob tshuaj txhua lub lis piam). Txawm li cas los xij, ntau dua permeability (high flux) daim nyias nyias, xws li polysulfone, ntshiab 25-50% ntawm cov tshuaj.
Tsis tas li ntawd, hom kab mob dab tsi uas vancomycin kho? Vancomycin . Vancomycin yog ib qho tshuaj tua kab mob siv rau kho ib tus lej kab mob kab mob . Nws yog pom zoo siv intravenously raws li ib tug kev kho mob rau cov tawv nqaij nyuaj kab mob , ntshav kab mob , endocarditis, pob txha thiab pob qij txha kab mob , thiab meningitis tshwm sim los ntawm methicillin-resistant Staphylococcus aureus.
Ua raws li qhov xav tau, pes tsawg feem pua ntawm vancomycin raug tshem tawm los ntawm kev lim ntshav?
40%
Vancomycin mechanism ntawm kev txiav txim yog dab tsi?
Vancomycin . Mechanism ntawm Action : inhibits cell phab ntsa synthesis los ntawm kev khi rau D-Ala-D-Ala davhlau ya nyob twg ntawm cov saw peptide loj hlob thaum lub sij hawm cell phab ntsa synthesis, ua rau inhibition ntawm transpeptidase, uas tiv thaiv ntxiv elongation thiab cross-linking ntawm peptidoglycan matrix (saib glycopeptide pharm).
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