Ubiquinone ua dab tsi hauv cov saw hlau thauj khoom?
Ubiquinone ua dab tsi hauv cov saw hlau thauj khoom?

Video: Ubiquinone ua dab tsi hauv cov saw hlau thauj khoom?

Video: Ubiquinone ua dab tsi hauv cov saw hlau thauj khoom?
Video: Qhia txhais 50 zaj npau suav tias yog dab tsi part 3 15 Sep 2019 2024, Lub peb hlis ntuj
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Ubiquinone (coenzyme Q) yog ib qho lipophilic metabolite uas ua haujlwm hauv lub cev electron thauj saw Nyob rau hauv lub plasma daim nyias nyias ntawm prokaryotes, thiab sab hauv mitochondrial daim nyias nyias ntawm eukaryotes, sib nrug los ntawm nws lub luag hauj lwm raws li ib tug antioxidant thiab nyob rau hauv lub regeneration ntawm tocopherols.

Ib yam li ntawd, nws tau nug, dab tsi ua haujlwm ntawm cytochrome C thiab ubiquinone?

Kev ua haujlwm ntawm Q-cytochrome c oxidoreductase yog txhawm rau txhawm rau hloov cov electrons los ntawm QH.2 oxidized cytochrome c (cyt c), dej-soluble protein ntau , thiab concomitantly tso cov protons tawm ntawm mitochondrial matrix. Q-cytochrome c oxidoreductase yog ib qho dimer nrog txhua lub monomer uas muaj 11 subunits (Daim duab 18.15).

Kuj Paub, puas yog ubiquinone ib qho khoom siv hluav taws xob? Ubiquinone muaj peev xwm txo qis dua li NADH-Q reductase. Li no NADH-Q reductase ua ob qho tib si electron cab kuj thiab lub twj tso kua mis proton. Ubiquinone yog ib electron cab kuj nkaus xwb; nws tsis yog lub twj tso kua mis proton. Yog li ntawd, ubiquinone tshuaj tsis nce H+ concentration nyob rau hauv lub interemembrane qhov chaw.

Yog li ntawd, ubiquinone siv rau dab tsi?

Ubiquinone yog ib yam khoom zoo li vitamin uas yog tsim nyob rau hauv lub cev. Ubiquinone Nws zoo li yuav siv tau lwm yam tshuaj raws li kev pab kho coenzyme Q-10 deficiency, los yog txo cov tsos mob ntawm mitochondrial disorders (cov xwm txheej uas cuam tshuam rau lub zog tsim tawm hauv cov hlwb ntawm lub cev).

CoQ yog dab tsi hauv electron thauj saw?

Coenzyme Q10: CoQ ) yog qhov tseem ceeb hluav taws xob thiab proton carrier nyob rau hauv lub mitochondrial ua pa saw (MRC), hloov electrons los ntawm complexes I thiab II mus rau complex III (Crane li al., 1957) thiab pab rau ATP biosynthesis.

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