Video: DNA microarrays siv tau rau dab tsi?
2024 Tus sau: Stanley Ellington | [email protected]. Kawg hloov kho: 2023-12-16 00:17
A DNA microarray (tseem hu ua DNA chip los yog biochip) yog ib phau ntawm microscopic DNA cov chaw txuas mus rau qhov chaw ruaj khov. Cov kws tshawb fawb siv DNA microarrays ntsuas cov theem qhia ntawm ntau cov noob ib txhij los yog mus rau genotype ntau thaj tsam ntawm ib lub genome.
Tom qab ntawd, ib tug kuj yuav nug, vim li cas microarrays pab tau?
Los ntawm kev siv microarray thev naus laus zis, cov kws tshawb fawb tuaj yeem pib qhia cov noob muaj feem cuam tshuam nrog tus kab mob. Microarrays tau siv los soj ntsuam gene qhia nyob rau hauv ib qho qauv los yog los sib piv cov gene qhia nyob rau hauv ob hom cell sib txawv los yog cov ntaub so ntswg kuaj, xws li cov ntaub so ntswg noj qab nyob zoo thiab muaj kab mob.
Ib yam li ntawd, DNA microarrays ua li cas? Cov DNA microarray yog ib lub cuab yeej siv los txiav txim seb qhov DNA los ntawm ib tus neeg muaj kev hloov pauv hauv cov noob xws li BRCA1 thiab BRCA2. Lub nti muaj ib lub khob me me uas ntim hauv cov yas. Qee lub tuam txhab tsim khoom microarrays siv txoj kev zoo ib yam li cov siv los ua lub computer microchips.
Ib yam li ntawd, tib neeg nug, microarrays siv li cas hauv kev tshawb fawb qog noj ntshav?
cDNA microarrays yog tsim los ntawm kev pom cDNAs, feem ntau yog PCR-amplified sequences los ntawm cov tsev qiv ntawv kab mob, mus rau iav slides (25). cDNA microarrays suav nrog ntev DNA molecules immobilized ntawm cov khoom nto thiab feem ntau siv rau kev soj ntsuam loj thiab kev kawm qhia.
mRNA yog dab tsi?
Messenger RNA ( mRNA ) Messenger RNA ( mRNA ) yog ib leeg-stranded RNA molecule uas yog ntxiv rau ib qho ntawm DNA strands ntawm cov noob. Cov mRNA yog RNA version ntawm cov noob uas tawm hauv lub cell nucleus thiab txav mus rau cytoplasm qhov twg cov proteins ua.
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