Muaj pes tsawg ATP raug tsim nyob rau hauv txoj kev pentose phosphate?
Muaj pes tsawg ATP raug tsim nyob rau hauv txoj kev pentose phosphate?

Video: Muaj pes tsawg ATP raug tsim nyob rau hauv txoj kev pentose phosphate?

Video: Muaj pes tsawg ATP raug tsim nyob rau hauv txoj kev pentose phosphate?
Video: Pentose Phosphate Pathway - Regulation, Purpose and Importance in Human Health 2024, Hlis ntuj nqeg
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Qhov tseeb enzyme ntawm cov txoj kev yog 6-phosphogluconate dehydrogenase. Tom qab cleavage ntawm lub pentose phosphate feem ntau tsim tawm glyceraldehyde 3- phosphate thiab acetate los yog acetyl phosphate (nyob ntawm seb lub enzyme system). Cov net tawm los ntawm ATP rau qhov no txoj kev feem ntau tsuas yog 1 ATP rau glucose molecule.

Yog li ntawd, puas yog pentose phosphate txoj kev tsim ATP?

Qhov no txoj kev , npe Pentose Phosphate Txoj Kev , yog tshwj xeeb vim tsis muaj zog nyob rau hauv daim ntawv ntawm ATP , los yog adenosine triphosphate, yog tsim tawm los yog siv nyob rau hauv no txoj kev.

Qhov thib ob, pes tsawg ATP raug tsim nyob rau hauv HMP shunt? Hauv HMP shunt, 12 khub ntawm hydrogen atoms thaum kawg hloov mus rau oxygen yielding 12 3 = 36 ATP. Ntawm no, 1 ATP yog siv los hloov ib qho molecule ntawm dawb qabzib-6 phosphate. Li no, cov txiaj ntsig tau yog 35 ATP uas piv tau zoo nrog 38 ATP tau los ntawm glycolysis thiab TCA lub voj voog.

Tom qab ntawd, pes tsawg Nadph raug tsim nyob rau hauv pentose phosphate txoj kev?

Cov tshuaj tiv thaiv ua ntej tawm los ntawm ob lub molecules ntawm NADPH thiab ib qho molecule ntawm ribose 5- phosphate rau txhua molecule ntawm qabzib 6- phosphate oxidized. Txawm li cas los xij, ntau hlwb xav tau NADPH rau reductive biosyntheses ntau ntau tshaj lawv xav tau ribose 5- phosphate rau kev koom ua ke rau hauv nucleotides thiab nucleic acids.

Dab tsi yog tsim nyob rau hauv pentose phosphate txoj kev?

Cov pentose phosphate txoj kev (tseem hu ua phosphogluconate txoj kev thiab hexose monophosphate shunt) yog ib qho metabolic txoj kev parallel rau glycolysis. Nws tsim NADPH thiab pentoses (5-carbon qab zib) thiab riwb 5 - phosphate , ib tug precursor rau synthesis ntawm nucleotides.

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