Lub hom phiaj tseem ceeb ntawm kev tsim tshuaj rational yog dab tsi?
Lub hom phiaj tseem ceeb ntawm kev tsim tshuaj rational yog dab tsi?

Video: Lub hom phiaj tseem ceeb ntawm kev tsim tshuaj rational yog dab tsi?

Video: Lub hom phiaj tseem ceeb ntawm kev tsim tshuaj rational yog dab tsi?
Video: Dr. Txawj teev vang - ๐Ÿ’˜๐Ÿ’ž๐Ÿ’ž Qhov Tseem ceeb Ntawm Kev cai Raus dej [ MV2 ~ 2021 ] 2024, Kaum ib hlis
Anonim

Lus Nug: Dab tsi yog Lub Hom Phiaj Tseem Ceeb Ntawm Kev Tsim Tshuaj Siv Tshuaj ? A) Ua kom luv luv Drug Discovery Txheej txheem B) Kom phim cov tshuaj nrog cov noob hloov pauv ntawm cov neeg mob C) Kom txo qis cov kev mob tshwm sim tsis xav tau D) Nrhiav Tshiab Tshuaj Cov Kev Kho Mob Rau Lub Hom Phiaj Cov Kab Mob Tsis Muaj Kab Mob.

Tsis tas li ntawd, lub hom phiaj tseem ceeb ntawm kev tsim tshuaj siv tshuaj tsim nyog yog dab tsi?

Tsim kom muaj kev txhawb nqa se yog qhov kev pom zoo los ntawm National Academy of Sciences txhawm rau txo cov neeg saib mob tsis txaus. Lub Tsev Hais Plaub Qib Siab hauv Teb Chaws Asmeskas tau muab faib ua cov kab ideological.

Qhov thib ob, cov txheej txheem dab tsi yog siv hauv kev tsim tshuaj? Ob txoj kev siv ntau tshaj plaws rau kev txiav txim siab peb-dimensional qauv ntawm cov hom phiaj protein rau cov tshuaj yog X-ray crystallography thiab nuclear magnetic resonance spectroscopy . Novel high-throughput technologies nyob rau hauv cov tshuaj nrhiav pom uas siv cov tswv yim no yuav tham txog.

Tsis tas li ntawd, dab tsi yog txhais los ntawm kev tsim tshuaj rational?

Tshuaj tsim , feem ntau hu ua rational tshuaj tsim los yog yooj yim rational tsim , yog cov txheej txheem ntawm kev nrhiav cov tshuaj tshiab raws li kev paub txog lub hom phiaj lom neeg. Lub ntsiab lus tseeb dua yog ligand tsim (ie, tsim ntawm ib lub molecule uas yuav khi nruj rau nws lub hom phiaj).

Dab tsi yog ligand-based tshuaj tsim?

Ligand Based Drug Design . Ligand raws li tshuaj tsim yog ib txoj hauv kev siv thaum tsis muaj cov ntaub ntawv 3D receptor thiab nws tso siab rau kev paub txog cov molecules uas khi rau lub hom phiaj lom neeg nyiam.

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