Dab tsi yog proteasome hauv biology?
Dab tsi yog proteasome hauv biology?

Video: Dab tsi yog proteasome hauv biology?

Video: Dab tsi yog proteasome hauv biology?
Video: Nyiaj yog dab tsi? 2024, Kaum ib hlis
Anonim

Proteasome : Ib qho protein degradation "tshuab" nyob rau hauv lub cell uas zom tau ntau yam proteins rau hauv luv luv polypeptides thiab amino acids. Cov proteasome nws tus kheej yog tsim los ntawm cov protein. Nws yuav tsum tau ATP ua haujlwm. Tib neeg lub xov tooj muaj txog 30,000 proteasomes.

Hauv qhov no, proteasomes ua dab tsi?

Proteasomes yog protein complexes uas degrade unneeded los yog puas cov proteins los ntawm proteolysis, ib tug tshuaj tiv thaiv uas lov peptide bonds. Proteasomes muaj nyob rau hauv tag nrho cov eukaryotes thiab archaea, thiab nyob rau hauv ib co kab mob. Hauv eukaryotes, proteasomes nyob rau hauv lub nucleus thiab nyob rau hauv lub cytoplasm.

Tsis tas li ntawd, muaj pes tsawg proteasomes nyob hauv ib lub cell? 20S proteasomes Nws yog lub luag haujlwm rau kev ua haujlwm ntawm proteolytic proteasomes thiab muaj li ntawm 28 subunits teem raws li lub tog raj kheej muaj plaub heteroheptameric rings nrog ib tug α17

Tom qab ntawd, lo lus nug yog, dab tsi yog ubiquitin proteasome?

Cov Ubiquitin Proteasome Pathway (UPP) yog lub luag haujlwm tseem ceeb rau cov protein catabolism hauv cov tsiaj txhu cytosol thiab nucleus. Cov kev tswj hwm zoo UPP cuam tshuam rau ntau yam ntawm cov txheej txheem ntawm tes thiab cov txheej txheem substrates thiab qhov tsis xws luag hauv cov kab ke tuaj yeem ua rau muaj kev cuam tshuam ntawm ntau yam kab mob tseem ceeb ntawm tib neeg.

ubiquitin yog dab tsi thiab nws txoj haujlwm yog dab tsi?

Ubiquitin yog ib qho protein me me uas muaj nyob hauv yuav luag tag nrho cov cellular cov ntaub so ntswg hauv tib neeg thiab lwm yam kab mob eukaryotic, uas pab tswj cov txheej txheem ntawm lwm cov proteins hauv lub cev.

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